A Systematic Evaluation of Immune Response and Plaque Microenvironment Variation in Alzheimer’s Disease

Alzheimer’s disease (AD) – the most prevalent form of dementia – is associated with defining histopathological features that include amyloid-beta (Aβ) plaque deposition and tau protein aggregation, accompanied by synaptic loss, neuronal death, and cognitive decline. The neuropathological changes in...

/ August 5, 2019

“In sickness and in health”: how individual immune response variability in health may influence how we respond to illness and therapy.

Thomas Fuller once said:  "Health is not valued till sickness comes." Well, that may not be true anymore. It turns out that the key to successful disease management strategies may lie with a better understanding of individual immune response variabilities...

/ July 29, 2019

Mapping the miRNA-mRNA Interactome in Multiple System Atrophy

A rapidly developing and fatal neurodegenerative disorder, MSA is frequently misdiagnosed or undetected until later stages due to its systemic nature, undefined etiopathogenesis, and multifaceted clinical presentation. In an attempt to unravel molecular changes in MSA, scientists from UC San...

/ July 22, 2019

GenCast for Genetic Engineering and Biotechnology News

NanoString Podcast Episode #1 /wp-content/uploads/2019/07/Nanostring-Podcast-Final2.mp3 Welcome to GenCast, a sponsored podcast series brought to you by Genetic Engineering and Biotechnology News. [00:00:07] I'm your host, Jeff Buguliskis. We often take for granted that we live in a three-dimensional world possessing...

/ July 15, 2019

Q&A with Dr. Lisa Butterfield, PhD: Cancer Vaccines & Adoptive Cell Transfer

Dr. Lisa Butterfield, PhD recently joined the Parker Institute for Cancer Immunotherapy as Vice President focusing on cell therapies while she continues her independent cancer vaccine research as an Adjunct Professor of Microbiology and Immunology at the University of California,...