All posts by Amal Katrib

A Strategic Attack Against Neurological Diseases

Neurological diseases are often multifactorial, brought on by a genetic and environmental tug-of-war and resulting in multifaceted clinical presentations. Such etiological complexity has hindered treatment progress and has necessitated well-thought-out and systematic strategies of attack to mitigate their global burden....

/ September 3, 2019

Experts Discuss Digital Spatial Profiling in Immuno-Oncology

The selective efficacy of immunotherapies continues to provide impetus for innovative solutions that can facilitate a deeper molecular interrogation of cancer biology. Researchers are increasingly adopting high-throughput technologies that capture morphological details, to elucidate cell-matrix adhesive interactions and their governance...

/ August 26, 2019

A Systematic Evaluation of Immune Response and Plaque Microenvironment Variation in Alzheimer’s Disease

Alzheimer’s disease (AD) – the most prevalent form of dementia – is associated with defining histopathological features that include amyloid-beta (Aβ) plaque deposition and tau protein aggregation, accompanied by synaptic loss, neuronal death, and cognitive decline. The neuropathological changes in...

/ August 5, 2019

Mapping the miRNA-mRNA Interactome in Multiple System Atrophy

A rapidly developing and fatal neurodegenerative disorder, MSA is frequently misdiagnosed or undetected until later stages due to its systemic nature, undefined etiopathogenesis, and multifaceted clinical presentation. In an attempt to unravel molecular changes in MSA, scientists from UC San...

/ July 22, 2019

New Biology-Driven Drug Discoveries Needed for Treating of Alzheimer’s

Alzheimer’s disease (AD) is a slowly progressing neurodegenerative disorder that affects millions of people worldwide, leaving behind an immense psychological, emotional, and financial burden on patients, caregivers, and healthcare systems. There are no existing therapies to prevent the onset or...

/ June 17, 2019