Month: August 2019

Experts Discuss Digital Spatial Profiling in Immuno-Oncology

The selective efficacy of immunotherapies continues to provide impetus for innovative solutions that can facilitate a deeper molecular interrogation of cancer biology. Researchers are increasingly adopting high-throughput technologies that capture morphological details, to elucidate cell-matrix adhesive interactions and their governance...

/ August 26, 2019

Q&A with Dr. Maureen McGargill, PhD: The Immune System’s Fine Line Between Health and Harm

Dr. McGargill earned her PhD at the University of Minnesota in Dr. Kristin Hogquist’s lab. There she studied T cell development, focusing on how autoreactive T cells are deleted during development. As a postdoc at the University of California, San...

miRNA Profiling in Malignant Melanoma: Making “Australia’s National Cancer” Obsolete.

Australia is a sun-worshipping country, the world capital for beautiful beaches, athletic surfers, cute marsupials, and the occasional weird-looking animal. But it is also the capital for something less pleasant: skin cancer. In fact, at least two in three Australians...

/ August 12, 2019

A Systematic Evaluation of Immune Response and Plaque Microenvironment Variation in Alzheimer’s Disease

Alzheimer’s disease (AD) – the most prevalent form of dementia – is associated with defining histopathological features that include amyloid-beta (Aβ) plaque deposition and tau protein aggregation, accompanied by synaptic loss, neuronal death, and cognitive decline. The neuropathological changes in...

/ August 5, 2019