Month: March 2017
Characterizing Severe Autoimmune Toxicities Associated with Checkpoint Inhibitor Therapies
Immune checkpoint inhibitors (ICI) have emerged as powerful tools against cancer but in some cases have caused inflammation of organ systems that contributed to morbidity or mortality in patients. The molecular underpinnings of toxicities from immune checkpoint inhibitors are not...
Monitoring Clinically Actionable Proteins- A Q&A with Gordon Mills, MD Anderson Cancer Center
NanoString sat down with Gordon Mills, M.D., Ph.D., Chair of Systems Biology Department at MD Anderson Cancer Center in Houston and lead developer of The Cancer Proteome Atlas (TCPA), to talk about the value of cataloging proteins and the future...
The IO Revolution, Part 3 of 4: The Role of the Tumor in the Cancer Immunity Cycle
Part one of this four-part series looked at how host, tumor, and environmental factors shape tumor-immune system interactions. Part two further examined the role of the host, and in this blog, we consider the role of the tumor in the...