Resolving the complexity of autoimmune diseases: challenges and solutions

Chronic inflammatory diseases are life-long debilitating illnesses with increased mortality and high healthcare costs for therapy and care. These are systemic conditions characterized by activation of either the adaptive immune system—rheumatoid arthritis, lupus, multiple sclerosis— or the innate immune system—Crohn’s...

/ September 16, 2019

GeoMx™ Digital Spatial Profiler: Q&A with Trieu My Van, PhD., NKI, Netherlands Cancer Institute, Christian Blank Lab

https://www.youtube.com/watch?v=M5xfd143_a0&feature=youtu.be What was the most surprising thing about using the GeoMx DSP platform?I was quite surprised about the high amount of data that's coming out of the platform from only a single FFPE tissue. This allows us to get better...

/ September 9, 2019

A Strategic Attack Against Neurological Diseases

Neurological diseases are often multifactorial, brought on by a genetic and environmental tug-of-war and resulting in multifaceted clinical presentations. Such etiological complexity has hindered treatment progress and has necessitated well-thought-out and systematic strategies of attack to mitigate their global burden....

/ September 3, 2019

Experts Discuss Digital Spatial Profiling in Immuno-Oncology

The selective efficacy of immunotherapies continues to provide impetus for innovative solutions that can facilitate a deeper molecular interrogation of cancer biology. Researchers are increasingly adopting high-throughput technologies that capture morphological details, to elucidate cell-matrix adhesive interactions and their governance...

/ August 26, 2019

Q&A with Dr. Maureen McGargill, PhD: The Immune System’s Fine Line Between Health and Harm

Dr. McGargill earned her PhD at the University of Minnesota in Dr. Kristin Hogquist’s lab. There she studied T cell development, focusing on how autoreactive T cells are deleted during development. As a postdoc at the University of California, San...